Quinolines and derivatives
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Filtered Search Results
Ambeed 4Aminoisophthalic acid
4-Aminoisophthalic acid, 33890-03-8, 98%
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Ambeed 5Bromo2methoxypyrimidine
5-Bromo-2-methoxypyrimidine, 14001-66-2, 98%
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Ambeed Methyl 2 triphenylphosphoranyl
Methyl 2-(triphenylphosphoranylidene)acetate, 2605-67-6, 98%
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Ambeed 3Aminopiperidine2 6dione
3-Aminopiperidine-2,6-dione, 2353-44-8, 98%
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Ambeed 3 4Chlorophenyl N pyridin4ylme
3-(4-Chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide, 915385-81-8, 98%
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Cambridge Isotope Laboratories 1 2 3 4 6 7-HexaCN (PCN-66) (unlabeled) 100 ug/mL in nonane 1 mL
1 2 3 4 6 7-HexaCN (PCN-66) (unlabeled) 100 ug/mL in nonane 1 mL
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Medchemexpress LLC (1E)-CFI-400437 dihydrochloride | 1247000-76-5 | 98.0% | 565.49 | 5 MG
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(1E)-CFI-400437 dihydrochloride is a potent PLK4 inhibitor with high selectivity. It also inhibits Aurora A, Aurora B, KDR, and FLT-3, demonstrating antiproliferative activity. This compound has shown effectiveness in a mouse xenograft model of tumor growth.
- Potent PLK4 inhibitor with IC50 of 0.6 nM
- Selective against other PLK family members
- Inhibits Aurora A, Aurora B, KDR, and FLT-3
- Exhibits antiproliferative activity
- Effective in mouse xenograft models of tumor growth
- Plasma protein binding is 99%
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Medchemexpress LLC Amino-PEG12-amine | 361543-12-6 | HY-133327 | 99.9% | 588.73 | 250 MG
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Amino-PEG12-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are molecules with two different ligands connected by a linker: one for an E3 ubiquitin ligase and another for a target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used as a PEG-based PROTAC linker
- Enables synthesis of PROTACs
- Facilitates selective degradation of target proteins
- Appears as a colorless to off-white solid-liquid mixture
- Has a purity of 99.92%
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Medchemexpress LLC Azido-PEG12-amine | 2803478-25-1 | 98.0% | 614.73 g/mol | C26H54N4O12 | 50 MG
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Azido-PEG12-amine is a PEG12 linker with an azide group at one terminus and a primary amine at the other, designed for bioconjugation and click chemistry applications.
- Azide functionality enables copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Primary amine enables conjugation to activated carboxylates such as NHS esters.
- Molecular weight approximately 614.73 g/mol; formula C26H54N4O12.
- High purity by NMR (typically 98.0%).
- Water-soluble PEG12 linker suitable for linker synthesis, PROTACs, and ADCs.
- Store sealed at 4°C, protect from moisture and light.
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Cayman Chemical 8 9DiHETE Fatty Acids and Deri
A major metabolite of EPA; produced in liver microsomes by CYP450 monooxygenases
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Medchemexpress LLC 6,8-Diprenylorobol | 66777-70-6 | 1 MG
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6,8-Diprenylorobol is a prenylated isoflavone isolated from the leaves of *Cudrania tricuspidata*. It exhibits an antiproliferative effect and induces apoptosis by activating p53 and generating reactive oxygen species (ROS). It has shown to inhibit proliferation in LoVo and HCT15 cells in a dose- and time-dependent manner and also regulates MAPKs.
- Exhibits antiproliferative effect
- Induces apoptosis by activating p53
- Generates reactive oxygen species (ROS)
- Inhibits proliferation in LoVo and HCT15 cells
- Regulates MAPKs in LoVo and HCT15 cells
- Increases ROS levels in LoVo and HCT15 cells
- Inhibits LPS-induced nitric oxide production in RAW264.7 cells
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Medchemexpress LLC m-PEG11-amine | 854601-60-8 | 515.64 g/mol | C23H49NO11 | 100 MG
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m-PEG11-amine is a PEG-based linker bearing a terminal amine used as a cleavable linker in antibody-drug conjugates (ADCs) and as a PROTAC linker or PEG spacer in conjugation chemistry. It provides a water-soluble spacer that facilitates conjugation to activated esters, carboxylic acids, and other reactive groups, improving solubility and flexibility of the resulting bioconjugates.
- PEG-based linker with a terminal primary amine for conjugation
- Used as a cleavable linker in antibody-drug conjugates (ADCs)
- Suitable as a PROTAC linker or PEG spacer in conjugation chemistry
- Water-soluble spacer improves solubility and flexibility of conjugates
- Available in multiple sizes for research-scale synthesis
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Medchemexpress LLC M-PEG12-amine | 1977493-48-3 | MFCD00131599 | ≥98.0% | 559.69 g/mol | C25H53NO12 | 100 MG
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m-PEG12-amine is a methoxy-terminated polyethylene glycol linker containing a 12-unit PEG chain and a terminal primary amine. It serves as a flexible, non-cleavable spacer for conjugation chemistry in linker and ADC/PROTAC synthesis.
- Methoxy-terminated PEG chain, 12 units.
- Terminal primary amine suitable for amide or carbamate coupling.
- Molecular weight approximately 559.7 g/mol; formula C25H53NO12.
- High purity (≥98%) appropriate for research and synthesis workflows.
- Supplied in small-scale quantities suitable for laboratory use.
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Ambeed 1 1 Thiocarbonylbis pyridin2 1
1,1'-Thiocarbonylbis(pyridin-2(1H)-one), 102368-13-8, 95%
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Medchemexpress LLC Quin C1 | 786706-21-6 | 98.5% | 445.51 g/mol | C26H27N3O4 | 5 MG
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Quin C1 is a small-molecule agonist of formyl peptide receptor 2 (FPR2/ALX) used in laboratory research to study inflammatory signaling. It is supplied as a high-purity solid intended for in vitro and in vivo experiments, with recommended cold-chain storage for long-term stability.
- Small-molecule FPR2/ALX agonist for modulation of inflammatory responses.
- High purity suitable for biochemical and cellular assays.
- Supplied as a powder with recommended cold storage to preserve stability.
- Available in multiple milligram pack sizes for experimental flexibility.
- Includes datasheet, certificate of analysis, and safety data for reproducible use.
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